Results of a prospective pilot trial on mobility after whole body vibration in children and adolescents with osteogenesis imperfecta
OBJECTIVE: To evaluate the effect of whole body vibration on the mobility of long-term immobilized children and adolescents with a seve...
A structural approach to the assessment of fracture risk in children and adolescents with chronic kidney disease
Children with chronic kidney disease (CKD) have multiple risk factors for impaired accretion of trabecular and cortical bone. CKD durin...
Can bisphosphonate treatment be stopped in a growing child with skeletal fragility
SUMMARY: Cyclical pamidronate therapy in a 2-year-old child with skeletal fragility resulted in remodelling of vertebral fractures and ...
Musculoskeletal abnormalities of the tibia in juvenile rheumatoid arthritis
OBJECTIVE: To characterize local bone geometry, density, and strength, using peripheral quantitative computed tomography (pQCT), compar...
Calcium supplementation and weight bearing physical activity–do they have a combined effect on the bone density of pre-pubertal children
The adaptation of bone to exercise has been shown to be modified by dietary calcium intake. The aim of this randomised controlled trial...
Annual change in bone mineral density in predialysis patients with chronic renal failure: significance of a decrease in serum 1,25-dihydroxy-vitamin D
Bone disease occurs in the predialysis phase of chronic renal failure (CRF). The aim of this study was to examine how a decrease in ren...
Material matters: a mechanostat-based perspective on bone development in osteogenesis imperfecta and hypophosphatemic rickets
This perspective paper presents a hypothesis that links abnormalities of bone material with densitometric findings in two congenital me...
Growth in early life predicts bone strength in late adulthood: the Hertfordshire Cohort Study
Infant growth is a determinant of adult bone mass, and poor childhood growth is a risk factor for adult hip fracture. Peripheral quanti...
Sex steroid levels and cortical bone size in young men are associated with a uridine diphosphate glucuronosyltransferase 2B7 polymorphism (H268Y)
CONTEXT: Sex steroids are involved in the regulation of pubertal cortical bone expansion in males. In vitro studies have indicated that...