Here an octogenarian voice from the past argues that the physiology of fascia, ligaments and tendons has strong and useful analogs in s...
Perspective: genetic and hormonal roles in bone disorders: insights of an updated bone physiology
In 1997 Professor J. Gorski suggested endocrinology needed new paradigms (Endocrine News 1997; 22:4,12). 'Connecting the dots' between ...
On the strength-safety factor (SSF) for load-bearing skeletal organs
The strength of healthy postnatal mammalian load-bearing bones, growth plates, joints, fascia, ligaments and tendons exceeds the minimu...
On the pathogenesis of osteogenesis imperfecta: some insights of the Utah paradigm of skeletal physiology
The pathogenesis of osteogenesis imperfecta (OI) baffled physiologists and physicians for over a century. Most past efforts to explain ...
Why should many skeletal scientists and clinicians learn the Utah paradigm of skeletal physiology
Adding later facts and ideas to a universally accepted '1960 paradigm' of skeletal physiology led to the still-evolving 'Utah paradigm'...
The Utah paradigm on animal models of skeletal disorders: quo vadis
Skeletal disorders that need effective studies in suitable animal models include 'osteoporosis', arthroses and hard and soft tissue hea...
Why the ISMNI and the Utah paradigm? Their role in skeletal and extraskeletal disorders
Besides bringing problems, aging can let the mind's eye see more clearly than before, and it can let us express ourselves better. As ag...
The Utah paradigm of skeletal physiology: an overview of its insights for bone, cartilage and collagenous tissue organs
In a 1960 paradigm of skeletal physiology, effector cells (chondroblasts, fibroblasts, osteoblasts, osteoclasts, etc.) regulated by non...
Variation in the density of the femoral diaphysis with age
1. A detailed study of density variations with age in cortical bone samples from different areas of the femoral diaphysis has been carr...
Bone growth in length and width: the Yin and Yang of bone stability
Bone growth in length is primarily achieved through the action of chondrocytes in the proliferative and hypertrophic zones of the growt...