Health effects associated with the Great Lakes environment were assessed in adult herring gulls (Larus argentatus) in the early 1990s, ...
Increased cortical remodeling after osteotomy causes posttraumatic osteopenia
Following a fracture, substantial bone mineral loss can occur at the affected limb. The aim of this study was to analyze the changes in...
Effects of estrogen receptor alpha- and beta-selective substances in the metaphysis of the tibia and on serum parameters of bone and fat tissue metabolism of ovariectomized rats
The functions of estrogen receptors (ER) alpha and beta (ER-alpha and beta) in bone and fat tissue are not precisely described. Therefo...
Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling
INTRODUCTION: It has been widely assumed that osteoclasts play a pivotal role during the entire process of fracture healing. Bisphospho...
Bax deficiency in mice increases cartilage production during fracture repair through a mechanism involving increased chondrocyte proliferation without changes in apoptosis
This study sought to determine the role of the pro-apoptotic gene, Bax, in fracture healing by comparing femoral fracture healing in Ba...
Hyperlipidemia impairs osteoanabolic effects of PTH
Epidemiological and in vitro studies have suggested that hyperlipidemia/oxidized phospholipids adversely affect bone. We recently found...
Alfacalcidol treatment increases bone mass from anticatabolic and anabolic effects on cancellous and cortical bone in intact female rats
It has been reported that alfacalcidol had an anticatabolic and anabolic effect on bone in ovariectomized and aged male rat models, but...
Beneficial effects of conjugated linoleic acid and exercise on bone of middle-aged female mice
Conjugated linoleic acids (CLA) are a group of polyunsaturated fatty acids that has recently been shown to have several beneficial effe...
Linkage screen for BMD phenotypes in male and female COP and DA rat strains
Because particular inbred strains of experimental animals are informative for only a subset of the genes underlying variability in BMD,...
Comparison of the healing of open tibial fractures covered with either muscle or fasciocutaneous tissue in a murine model
The objective of this study was to compare the effects of soft tissue coverage by either muscle or fasciocutaneous tissue on the healin...