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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Advantages of raloxifene over alendronate or estrogen on nonreproductive and reproductive tissues in the long-term dosing of ovariectomized rats

For the first time, raloxifene or alendronate was administered to rats immediately after ovariectomy for 10 months and compared with es...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Raloxifene, tamoxifen, nafoxidine, or estrogen effects on reproductive and nonreproductive tissues in ovariectomized rats

For the first time, four well-characterized compounds from four distinct chemical classes were directly compared for efficacy and poten...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Effects of wortmannin analogs on bone in vitro and in vivo

The possible importance of phosphatidylinositol (PI) 3-kinase activity in bone resorption activity in vitro and in vivo were evaluated ...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Regional analysis of bone mineral density in the distal femur and proximal tibia using peripheral quantitative computed tomography in the rat In vivo

The use of peripheral quantitative computed tomography (pQCT) was investigated for the measurement of volumetric bone mineral density (...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Genetic variability in adult bone density among inbred strains of mice

More than 70% of the variability in human bone density has been attributed to genetic factors as a result of studies with twins, osteop...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Raloxifene preserves bone strength and bone mass in ovariectomized rats

We investigated the effects of raloxifene, a nonsteroidal benzothiophene, on bone strength in ovariectomized rats and compared them wit...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Comparative x-ray densitometry of bones from ovariectomized rats

Comparative analysis of dual energy x-ray absorptiometry (DXA) and quantitative computed tomography (QCT) with phantoms and rat bones s...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Assessing bone quantity by pQCT

We have tested the ability of the XCT960A to detect bone loss in OVX-rats, as well as bone gain in the proximal tibial metaphysis of he...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Effect of treatment for 3 months with human parathyroid hormone 1-34 peptide in ovariectomized cynomolgus monkeys (Macaca fascicularis)

Clinical data suggest that PTH may increase cancellous bone mass at the expense of cortical bone in human beings. In this study, the ef...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Treatment with growth hormone and IGF-I in growing rats increases bone mineral content but not bone mineral density

Human growth hormone (hGH) and insulin-like growth factor I (IGF-I) both stimulate bone formation and have been proposed as therapeutic...
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