Calcium absorption and bone loss in ovariectomized rats fed varying levels of dietary calcium
The following studies were undertaken to examine whether estrogen deficiency impairs calcium absorption in aged rats, and to determine ...
Food fractionation is a powerful tool to increase bone mass in growing rats and to decrease bone loss in aged rats: modulation of the effect by dietary phosphate
The incidence of osteoporotic fractures has been associated with low bone mass. To reduce this incidence, it is therefore important to ...
Targeted expression of calcitonin gene-related peptide to osteoblasts increases bone density in mice
The neuropeptide calcitonin gene-related peptide (CGRP) is concentrated in fine sensory nerve endings innervating all tissues, includin...
Application of automatic image segmentation to tibiae and vertebrae from ovariectomized rats
Automatic contextual segmentation algorithms were developed to objectively identify bone compartments in pQCT images of tibiae, femora,...
Morphometric analysis of gastrectomy-evoked osteopenia
Gastrectomy leads to osteopenia in the rat. The present study describes the effects of gastrectomy on bone morphology. Rats were subjec...
Biosynthetic human parathyroid hormone (1-34) effects on bone quality in aged ovariectomized rats
For the first time, PTH (1-34) was found to significantly affect bone quality, femora length, and body weight of aged, ovariectomized r...
Femoral neck is a sensitive indicator of bone loss in immobilized hind limb of mouse
The present study was carried out to evaluate a unilateral hind limb immobilization model in the mouse. The right legs of male mice (ag...
Circulating and skeletal insulin-like growth factor-I (IGF-I) concentrations in two inbred strains of mice with different bone mineral densities
Recent work has demonstrated differences in femoral bone mineral density between two common inbred strains of mice, C3H/HeJ (C3H) and C...
Effects of an inhibitor of cathepsin L on bone resorption in thyroparathyroidectomized and ovariectomized rats
The process of bone resorption by osteoclasts involves the dissolution of mineral salts and enzymatic degradation of the mainly collage...