Pre-Clinical Studies Archives | Page 29 of 40 | Novotec Medical & Stratec Medizintechnik

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Opposing changes in osteocalcin levels in bone vs serum during the acquisition of peak bone density in C3H/HeJ and C57BL/6J mice

Our knowledge of the developmental changes in the concentration of serum and bone osteocalcin (OC) is limited. To investigate the inter...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Mouse genetic model for bone strength and size phenotypes: NZB/B1NJ and RF/J inbred strains

The relationships of bone size, bone strength, and bone formation were investigated in two strains of mice, NZB/B1NJ and RF/J. Measurem...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage

The runt family transcription factor core-binding factor alpha1 (Cbfa1) is essential for bone formation during development. Surprisingl...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Common herbs, essential oils, and monoterpenes potently modulate bone metabolism

During our survey of herbs looking for activity on bone metabolism, we found that the dried leaves of sage strongly inhibit bone resorp...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

In vivo rat assay: bone remodeling and steroid effects on juvenile bone by pQCT quantification in 7 days

Anesthetized Sprague-Dawley weanling rats were scanned for bone mineral density (BMD) values after 7 days of treatment to determine whe...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Peripheral quantitative computed tomography for the detection of diabetic osteopathy: a study in the Goto-Kakizaki rat

RATIONALE AND OBJECTIVE: To assess the utility of dual energy x-ray absorptiometry (DEXA) and peripheral quantitative computed tomograp...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Evidence that anabolic effects of PTH on bone require IGF-I in growing mice

Although it has been established that PTH exerts potent anabolic effects on bone in animals and humans, the mechanism of PTH action on ...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Ablation of TRalpha2 and a concomitant overexpression of alpha1 yields a mixed hypo- and hyperthyroid phenotype in mice

Thyroid hormone governs a diverse repertoire of physiological functions through receptors encoded in the receptor genes alpha and beta,...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Rodent model for investigating the effects of estrogen on bone and muscle relationship during growth

It has been reported that in humans from about 11-12 years of age, bone mass begins to increase faster in girls than in boys with the s...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone/IGF-I excess in transgenic mice

Insulin-like growth factor-binding protein-2 (IGFBP-2) has been suggested to be a negative regulator of bone growth and maintenance. Th...

Opposing changes in osteocalcin levels in bone vs serum during the acquisition of peak bone density in C3H/HeJ and C57BL/6J mice

Mouse genetic model for bone strength and size phenotypes: NZB/B1NJ and RF/J inbred strains

High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage

Common herbs, essential oils, and monoterpenes potently modulate bone metabolism

In vivo rat assay: bone remodeling and steroid effects on juvenile bone by pQCT quantification in 7 days

Peripheral quantitative computed tomography for the detection of diabetic osteopathy: a study in the Goto-Kakizaki rat

Evidence that anabolic effects of PTH on bone require IGF-I in growing mice

Ablation of TRalpha2 and a concomitant overexpression of alpha1 yields a mixed hypo- and hyperthyroid phenotype in mice

Rodent model for investigating the effects of estrogen on bone and muscle relationship during growth

Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone/IGF-I excess in transgenic mice

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