Pre-Clinical Studies Archives | Page 24 of 40 | Novotec Medical & Stratec Medizintechnik

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice

IGF-binding protein-5 (IGFBP-5) is abundant in serum and bone during normal skeletal development, but levels decrease in osteoporosis. ...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Bone mineral density in male Baltic grey seal (Halichoerus grypus)

Bone mineral density (mg cm(-3)) was studied in male Baltic grey seals (4-23 years of age) by noninvasive computed tomography (pQCT). T...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Abnormal bone composition in female juvenile American alligators from a pesticide-polluted lake (Lake Apopka, Florida)

Reproductive disorders have been found in pesticide-exposed alligators living in Lake Apopka, Florida (USA). These disorders have been ...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Abnormal bone architecture and biomechanical properties with near-lifetime treatment of rats with PTH

Skeletal effects are described for near-lifetime treatment of young, female rats with recombinant human PTH (1-34) (PTH). Rats (5-8 wk ...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Local ex vivo gene therapy with bone marrow stromal cells expressing human BMP4 promotes endosteal bone formation in mice

BACKGROUND: Bone loss in osteoporosis is caused by an imbalance between resorption and formation on endosteal surfaces of trabecular an...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Increased cortical bone mineral content but unchanged trabecular bone mineral density in female ERbeta(-/-) mice

Ovariectomy in young, growing rodents results in decreased trabecular bone mineral density (BMD) and increased radial growth of the cor...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis

The b and c variants of fibroblast growth factor receptor 2 (FGFR2) differ in sequence, binding specificity, and localization. Fgfr2b, ...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Hindlimb unloading has a greater effect on cortical compared with cancellous bone in mature female rats

This study was designed to determine the effects of 28 days of hindlimb unloading (HU) on the mature female rat skeleton. In vivo proxi...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Determination of mechanical stiffness of bone by pQCT measurements: correlation with non-destructive mechanical four-point bending test data

Mechanical tests of bone provide valuable information about material and structural properties important for understanding bone patholo...

t2023est22nut0ss5zer

20 Jan 2025

20. January 2025

Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089)

Conditions of disuse in bed rest patients, as well as microgravity experienced by astronauts are accompanied by reduced mechanical load...

Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice

Bone mineral density in male Baltic grey seal (Halichoerus grypus)

Abnormal bone composition in female juvenile American alligators from a pesticide-polluted lake (Lake Apopka, Florida)

Abnormal bone architecture and biomechanical properties with near-lifetime treatment of rats with PTH

Local ex vivo gene therapy with bone marrow stromal cells expressing human BMP4 promotes endosteal bone formation in mice

Increased cortical bone mineral content but unchanged trabecular bone mineral density in female ERbeta(-/-) mice

A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis

Hindlimb unloading has a greater effect on cortical compared with cancellous bone in mature female rats

Determination of mechanical stiffness of bone by pQCT measurements: correlation with non-destructive mechanical four-point bending test data

Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089)

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