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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo

Statins potently inhibit 3-hydroxy-3-methylglutaryl-coenzyme A reductase, blocking downstream biosynthesis of isoprenoid lipids and cau...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

High impact exercise is more beneficial than dietary calcium for building bone strength in the growing rat skeleton

The benefits of impact exercise and dietary calcium on bone development are controversial. We used inbred rats under highly controlled ...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Effects of treatment with parathyroid hormone 1-84 on quantity and biomechanical properties of thoracic vertebral trabecular bone in ovariectomized rhesus monkeys

Osteoporosis is characterized by impaired bone quality leading to increased susceptibility to fracture, particularly of the thoracic sp...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Epistatic effects contribute to variation in BMD in Fischer 344 x Lewis F2 rats

To further delineate the factors underlying the complex genetic architecture of BMD in the rat model, a genome screen for epistatic int...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Genetic loci affecting bone structure and strength in inbred COP and DA rats

Previous studies have shown that the Copenhagen 2331 (COP) and Dark Agouti (DA) rats have significant differences in bone structure and...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Impact of pregnancy-associated plasma protein-a deletion on the adult murine skeleton

INTRODUCTION: The metalloproteinase, pregnancy-associated plasma protein-A (PAPP-A) functions to enhance local insulin-like growth fac...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Knee loading accelerates bone healing in mice

Knee loading is an anabolic loading modality that applies lateral loads to the knee. This study shows that loads applied to the proxima...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Relationships between densitometric and morphological parameters as measured by peripheral computed tomography and the compressive behavior of lumbar vertebral bodies from macaques (Macaca fascicularis)

STUDY DESIGN: The measured maximum compressive force and stress of lumbar vertebral bodies from cynomolgus monkeys were compared with p...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Semaphorin 3B is a 1,25-Dihydroxyvitamin D3-induced gene in osteoblasts that promotes osteoclastogenesis and induces osteopenia in mice

The vitamin D endocrine system is important for skeletal homeostasis. 1,25-Dihydroxyvitamin D(3) impacts bone indirectly by promoting ...
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t2023est22nut0ss5zer
20 Jan 2025
20. January 2025

Short-term changes in serum PINP predict long-term changes in trabecular bone in the rat ovariectomy model

Serum procollagen I N-terminal propeptide (PINP) is a sensitive bone formation marker in humans. We have developed a nonradioactive imm...
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