An in vivo rabbit model for cartilage trauma: a preliminary study of the influence of impact stress magnitude on chondrocyte death and matrix damage
OBJECTIVE: This study was designed to evaluate the postimpact response of the articular cartilage in the rabbit knee after a single tra...
In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) affects bone tissue in rhesus monkeys
Bone tissue is one of the target tissues for dioxins and dioxin-like compounds. Therefore, the aim of this study was to investigate eff...
Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha
Osteoporosis and muscle frailty are important health problems in elderly men and may be partly related to biological androgen activity....
Percutaneous nonviral delivery of hepatocyte growth factor in an osteotomy gap promotes bone repair in rabbits: a preliminary study
Hepatocyte growth factor (HGF) was initially identified in cultured hepatocytes and subsequently reported to induce angiogenic, morphog...
Changes in subchondral bone mineral density and collagen matrix organization in growing horses
OBJECTIVE: The effects of growth and maturation on the mineral deposition and the collagen framework of equine subchondral bone (SCB) w...
The pairing of a selective estrogen receptor modulator, bazedoxifene, with conjugated estrogens as a new paradigm for the treatment of menopausal symptoms and osteoporosis prevention
The menopausal transition is associated with decreased ovarian function and concomitant decline in estrogen production, which may resul...
Fracture healing in mice deficient in plasminogen activator inhibitor-1
To evaluate the role of plasminogen activator inhibitor (PAI)-1, a key negative regulator of the plasmin system of extracellular matrix...
The Frozen Shoulder syndrome plus other evidence and the Utah Paradigm suggest the syndrome’s pathogenesis and new targets for collagenous tissue research.
Sometimes naturally occurring disorders combined with other evidence can provide a 'virtual laboratory' exercise that answers old quest...
In vivo human tendon mechanical properties: effect of resistance training in old age
Recent advances in ultrasound scanning have made it possible to obtain the mechanical properties of human tendons in vivo. Application ...
Adaptation of the tendon to mechanical usage
Tendons primarily function as contractile force transmitters, but their mechanical properties may change dependent upon their level of ...