Paricalcitol [19-nor-1,25-(OH)2D2] in the treatment of experimental renal bone disease
Paricalcitol is a less hypercalcemic vitamin D analog that has been shown to suppress secondary hyperparathyroidism and to prevent the ...
Regional distinctions in cortical bone mineral density measured by pQCT can predict alterations in material property at the tibial diaphysis of the Cynomolgus monkey
We examined whether regional differences in cortical bone mineral density (Ct.BMD) measured by peripheral quantitative computed tomogra...
Renal insufficiency-induced bone loss is associated with an increase in bone size and preservation of strength in rat proximal femur
Chronic renal insufficiency (CRI) results in phosphate retention and secondary hyperparathyroidism, the treatment of which is largely b...
IGF-I secretion by prostate carcinoma cells does not alter tumor-bone cell interactions in vitro or in vivo
BACKGROUND: IGF-I is an important growth and differentiative factor for osteoblasts and may have a role in defining prostate cancer ris...
Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts
Mature bone-resorbing osteoclasts (OCs) mediate excessive bone loss seen in several bone disorders, including osteoporosis. Here, we sh...
Digestible energy intake, dry matter digestibility and effect of increased calcium intake on bone parameters of grazing Thoroughbred weanlings in New Zealand
AIMS: To measure the nutritive value of pasture in terms of digestible energy intake (DEI) and dry matter (DM) digestibility, and the e...
Perinatal testosterone surge is required for normal adult bone size but not for normal bone remodeling
Although testosterone (T) has striking effects on mature skeletal size and structure, it is not clear whether this depends exclusively ...
Musculoskeletal responses of 2-year-old Thoroughbred horses to early training. 7. Bone and articular cartilage response in the carpus
AIM: To describe features of the morphology of the carpus, quantify the thickness of hyaline and calcified cartilage, and to describe t...
Musculoskeletal responses of 2-year-old Thoroughbred horses to early training. 6. Bone parameters in the third metacarpal and third metatarsal bones
AIM: To determine the effect of a known training regimen on the size and mineral content of the third metacarpal (Mc3) and third metata...
The use of micro-CT to evaluate cortical bone geometry and strength in nude rats: correlation with mechanical testing, pQCT and DXA
In both clinical and experimental settings, access to quantitative methods enabling the objective evaluation of cortical bone mass, str...