Specific effects of gamma-linolenic, eicosapentaenoic, and docosahexaenoic ethyl esters on bone post-ovariectomy in rats
Long chain polyunsaturated fatty acids (LCPUFAs) are involved in the regulation of bone metabolism. Increased dietary consumption of n-...
A technique for computed tomography (CT) of the foot in the standing horse
Computed tomography (CT) in equine orthopaedics is currently limited because of the price, availability, impossibility to transport the...
Replacement of bone marrow by bone in rat femurs: the bone bioreactor
During development and repair of bone, two distinct yet complementary mechanisms, intramembranous and endochondral, mediate new bone fo...
The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice
Estrogen (E) is critical for the maintenance of bone mass in both female and male mice and steroid receptor coactivator (SRC)-1 has bee...
TIEG-null mice display an osteopenic gender-specific phenotype
TGFbeta inducible early gene-1 (TIEG) was originally cloned from human osteoblasts (OB) and has been shown to play an important role in...
Continuous local infusion of fibroblast growth factor-2 enhances consolidation of the bone segment lengthened by distraction osteogenesis in rabbit experiment
Experimental tibial lengthening was achieved in 61 rabbits to examine the effect of continuous local infusion of recombinant human fibr...
Constrained tibial vibration in mice: a method for studying the effects of vibrational loading of bone
Vibrational loading can stimulate the formation of new trabecular bone or maintain bone mass. Studies investigating vibrational loading...
Contrasting effects of estradiol, testosterone and a black cohosh extract on density, mechanical properties and expression of several genes in the metaphysis of the tibia and on fat tissue of orchidectomized rats
Objectives: Orchidectomy (orx) of rats increases bone metabolism, the activity of osteoclasts more than of osteoblasts which results in...
Chemical mutagenesis induced two high bone density mouse mutants map to a concordant distal chromosome 4 locus
Phenotype-driven mutagenesis approach in the mouse holds much promise as a method for revealing gene function. Earlier, we have describ...
Urokinase plasminogen activator receptor affects bone homeostasis by regulating osteoblast and osteoclast function
The uPAR and its ligand uPA are expressed by both osteoblasts and osteoclasts. Their function in bone remodeling is unknown. We report ...