{"id":166534,"date":"2025-01-20T16:32:47","date_gmt":"2025-01-20T15:32:47","guid":{"rendered":"https:\/\/stratec-med.com\/literatur\/effects-of-an-omega-3-supplemented-high-protein-diet-in-combination-with-vibration-and-resistance-exercise-on-muscle-power-and-inflammation-in-old-adults-a-pilot-randomized-controlled-trial-2\/"},"modified":"2025-01-20T16:32:47","modified_gmt":"2025-01-20T15:32:47","slug":"effects-of-an-omega-3-supplemented-high-protein-diet-in-combination-with-vibration-and-resistance-exercise-on-muscle-power-and-inflammation-in-old-adults-a-pilot-randomized-controlled-trial-2","status":"publish","type":"literatur","link":"https:\/\/stratec-med.com\/en\/literature\/effects-of-an-omega-3-supplemented-high-protein-diet-in-combination-with-vibration-and-resistance-exercise-on-muscle-power-and-inflammation-in-old-adults-a-pilot-randomized-controlled-trial-2\/","title":{"rendered":"Effects of an Omega-3 Supplemented, High-Protein Diet in Combination with  Vibration and Resistance Exercise on Muscle Power and Inflammation in Old Adults:  A Pilot Randomized Controlled Trial."},"content":{"rendered":"<p>BACKGROUND: Inflammaging is considered to drive loss of muscle function. Omega-3  fatty acids exhibit anti-inflammatory properties. Therefore, we examined the  effects of eight weeks of vibration and home-based resistance exercise combined  with a whey-enriched, omega-3-supplemented diet on muscle power, inflammation and  muscle biomarkers in community-dwelling old adults. METHODS: Participants were  randomized to either exercise (3x\/week, n = 20), exercise + high-protein diet  (1.2-1.5 g\/kg, n = 20), or exercise + high-protein and omega-3-enriched diet (2.2  g\/day, n = 21). Muscle power (watt\/m(2)) and chair rise test (CRT) time (s) were  assessed via CRT measured with mechanography. Furthermore, leg strength (kg\/m(2))  and fasting concentrations of inflammatory (interleukin (IL-) 6, IL-10,  high-mobility group box-1 (HMGB-1)) and muscle biomarkers (insulin-like growth  factor (IGF-) 1, IGF-binding protein-3, myostatin) were assessed. RESULTS:  Sixty-one participants (70.6 +\/- 4.7 years; 47% men) completed the study. According  to generalized linear mixed models, a high-protein diet improved leg strength and  CRT time. Only IGF-1 increased with additional omega-3. Sex-specific analyses  revealed that muscle power, IL-6, IL-6\/IL-10 ratio, and HMGB-1 improved  significantly in the male high-protein, omega-3-enriched group only. CONCLUSION:  Vibration and home-based resistance exercise combined with a high-protein,  omega-3-enriched diet increased muscle power and reduced inflammation in old men,  but not in old women. While muscle biomarkers remained unchanged, a high-protein  diet combined with exercise improved leg strength and CRT time.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>BACKGROUND: Inflammaging is considered to drive loss of muscle function. Omega-3 fatty acids exhibit anti-inflammatory properties. Therefore, we examined the<\/p>\n","protected":false},"author":22,"parent":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false},"tags":[],"thema":[5924,5866,5860,5936,5886,5880,5856],"produktgruppe":[7527,5831,5827],"literatur_kategorie":[7221],"class_list":["post-166534","literatur","type-literatur","status-publish","format-standard","hentry","thema-clinical-studies","thema-diagnostics-using-leonardo-pqct","thema-leonardo-mechanography-en","thema-medical-application","thema-prevention","thema-pyhsitherapy-rehabilitation","thema-therapy-prevention-using-galileo","produktgruppe-galileo-en","produktgruppe-galileo-therapy","produktgruppe-leonardo-en","literatur_kategorie-clinical-studies"],"acf":[],"_links":{"self":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur\/166534","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur"}],"about":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/types\/literatur"}],"author":[{"embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/users\/22"}],"version-history":[{"count":0,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur\/166534\/revisions"}],"wp:attachment":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/media?parent=166534"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/tags?post=166534"},{"taxonomy":"thema","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/thema?post=166534"},{"taxonomy":"produktgruppe","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/produktgruppe?post=166534"},{"taxonomy":"literatur_kategorie","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur_kategorie?post=166534"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}