{"id":166218,"date":"2025-01-20T16:22:30","date_gmt":"2025-01-20T15:22:30","guid":{"rendered":"https:\/\/stratec-med.com\/literatur\/quantitative-peripheral-computed-tomography-to-measure-muscle-area-and-assess-lean-soft-tissue-mass-in-children-2\/"},"modified":"2025-01-20T16:22:30","modified_gmt":"2025-01-20T15:22:30","slug":"quantitative-peripheral-computed-tomography-to-measure-muscle-area-and-assess-lean-soft-tissue-mass-in-children-2","status":"publish","type":"literatur","link":"https:\/\/stratec-med.com\/en\/literature\/quantitative-peripheral-computed-tomography-to-measure-muscle-area-and-assess-lean-soft-tissue-mass-in-children-2\/","title":{"rendered":"Quantitative peripheral computed tomography to measure muscle area and assess lean soft tissue mass in children."},"content":{"rendered":"<p>BACKGROUND: Skeletal muscle is one of the main components of lean soft tissue mass (LSTM). Low levels in children affect locomotion, posture and increase the risk of metabolic syndrome. AIM: (1) To evaluate the association between cross-sectional muscle area (MCSA) of the lower left leg measured by quantitative peripheral computed tomography (pQCT) and total LSTM; namely, total left leg and  left lower leg LSTM assessed by dual-energy X-ray absorptiometry (DXA) in a group of children (2) to examine if MCSA is a predictor of LSTM (3) to determine the ability of pQCT to identify children with low LSTM. SUBJECTS AND METHODS: Lower left leg MCSA and LSTM were measured using pQCT and DXA, respectively, in 396 children. RESULTS: Statistically significant positive correlations were found between the lower leg MCSA- total LSTM (r(2) = .789), total leg LSTM (r(2) = .79), and lower leg LSTM (r(2) = .791) (p <.01). MCSA explained 64-68% of the variance in LSTM.ROC curves determined the capacity of the lower left leg MCSA to identify low LSTM in girls (AUC 0.95) and boys (AUC 0.87). CONCLUSIONS: Our results showed that lower left leg MCSA, measured using pQCT, could be a tool to  predict low LSTM in children.\n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>BACKGROUND: Skeletal muscle is one of the main components of lean soft tissue mass (LSTM). Low levels in children affect<\/p>\n","protected":false},"author":22,"parent":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false},"tags":[],"thema":[5924,5866],"produktgruppe":[5825],"literatur_kategorie":[7221],"class_list":["post-166218","literatur","type-literatur","status-publish","format-standard","hentry","thema-clinical-studies","thema-diagnostics-using-leonardo-pqct","produktgruppe-pqct-en","literatur_kategorie-clinical-studies"],"acf":[],"_links":{"self":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur\/166218","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur"}],"about":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/types\/literatur"}],"author":[{"embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/users\/22"}],"version-history":[{"count":0,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur\/166218\/revisions"}],"wp:attachment":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/media?parent=166218"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/tags?post=166218"},{"taxonomy":"thema","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/thema?post=166218"},{"taxonomy":"produktgruppe","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/produktgruppe?post=166218"},{"taxonomy":"literatur_kategorie","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur_kategorie?post=166218"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}