{"id":164772,"date":"2025-01-20T15:25:17","date_gmt":"2025-01-20T14:25:17","guid":{"rendered":"https:\/\/stratec-med.com\/literatur\/pqct-measures-of-bone-and-muscle-are-independently-associated-with-falls-in-women-a-principal-components-analysis-2\/"},"modified":"2025-01-20T15:25:18","modified_gmt":"2025-01-20T14:25:18","slug":"pqct-measures-of-bone-and-muscle-are-independently-associated-with-falls-in-women-a-principal-components-analysis-2","status":"publish","type":"literatur","link":"https:\/\/stratec-med.com\/en\/literature\/pqct-measures-of-bone-and-muscle-are-independently-associated-with-falls-in-women-a-principal-components-analysis-2\/","title":{"rendered":"pQCT measures of bone and muscle are independently associated with falls in women \u2013 a principal components analysis"},"content":{"rendered":"<p>BACKGROUND:<br \/>\nfalling is often a first step to generate sufficient energy for a fragility fracture fallers have been associated with poor muscle strength and low vitamin D levels fat within muscle has been suggested to reduce physical function leading to reduced torque acting on bone mid-shaft of lower leg experiences bending forces led by stabilizing muscle groups during gait and balancing with falls plantarflexor muscle volume previously shown to explain 64% of mid-tibial bone strength (Rantalainen et al, 2008)<br \/>\nMETHODOLOGY:<br \/>\nIntended population: Women = 50 years of age belonging to the local Canadian Multicentre Osteoporosis Study (CaMos) Hamilton, Ontario site were invited to participate.<br \/>\nCaMos is an ongoing, prospective cohort study of 9423 community-dwelling, randomly selected women &#038; men = 25 years of age at 9 Canadian cities. The original cohort was recruited in 1996-1997 through scientific random selection using residential telephone lists. CaMos objectives, methodology and sampling framework were detailed elsewhere (Kreiger et al. 1999, Can J Aging 18(3):12).<br \/>\nPrimary outcome: Falls (yes\/no) in last 12 months obtained from the CaMos database.<br \/>\nSUMMARY &#038; CONCLUSION:<br \/>\nBone endosteal and periosteal geometry plus muscle morphometry at the mid-calf enables identification of fallers<br \/>\nA poorer bone geometry may be indicative of a low degree of bone adaptation, reflecting low muscle torque resulting from high muscle fat \u2013 together predisposing individuals for falls<br \/>\nMeanwhile, bone geometry alone appeared to identify fallers independently of muscle morphometry<br \/>\nHaving high muscle fat not only prevents adequate strength for balance during falls, but may result in poorer bone quality that could be associated with higher fracture risk<\/p>\n","protected":false},"excerpt":{"rendered":"<p>BACKGROUND: falling is often a first step to generate sufficient energy for a fragility fracture fallers have been associated with<\/p>\n","protected":false},"author":22,"parent":0,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false},"tags":[1560,1559],"thema":[5870,5876,5888,5878,5882,5894,5886,5880,5900,5856],"produktgruppe":[5825],"literatur_kategorie":[7221],"class_list":["post-164772","literatur","type-literatur","status-publish","format-standard","hentry","tag-falls","tag-muslce-density","thema-basics","thema-diseases","thema-geriatrics","thema-medical-applications","thema-neurological-conditions","thema-osteoporosis","thema-prevention","thema-pyhsitherapy-rehabilitation","thema-stroke","thema-therapy-prevention-using-galileo","produktgruppe-pqct-en","literatur_kategorie-clinical-studies"],"acf":[],"_links":{"self":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur\/164772","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur"}],"about":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/types\/literatur"}],"author":[{"embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/users\/22"}],"version-history":[{"count":0,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur\/164772\/revisions"}],"wp:attachment":[{"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/media?parent=164772"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/tags?post=164772"},{"taxonomy":"thema","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/thema?post=164772"},{"taxonomy":"produktgruppe","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/produktgruppe?post=164772"},{"taxonomy":"literatur_kategorie","embeddable":true,"href":"https:\/\/stratec-med.com\/en\/wp-json\/wp\/v2\/literatur_kategorie?post=164772"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}